MARCONS stands for multiple antibiotic resistant coagulase negative Staph. MARCONS treatment is controversial, especially if MARCONS truly causes symptoms in individuals.
Normal Staphylococcus is ubiquitous in the environment including the nasal cavity of humans. Partly resistant Staph or what we call MRSA is becoming increasingly common and can colonize the nasal cavity and skin sometimes making it difficult to treat cellulitis. MARCONS is an organism that can be found in multiple hosts, however, those with CIRS/inflammatory response syndrome and low MSH are more susceptible to symptoms caused by by MARCONS (SM and ISEAI consensus statements). It is my belief and others that the more severe the CIRS, the more important to treat and eradicate MARCONS.
A few years ago, it was shown that colloidal silver and especially ASC200 were effective at treating MRSA topically. In 2016, Microbiologydx discovered in vitro that ASC200 worked on MARCONS. No, ASC200 does not induce skin coloring as suggested online which can occur with some forms of colloidal silver.
MARCONS is ubiquitous in the environment and not everyone will have symptom reduction with eradications of MARCONS. However, those with facial pain such as trigeminal neuralgia and chronic fatigue syndrome who live in an elevated mold environment (as proved by mold dna per testing) can benefit by eradication of MARCONS. In the past, we used BEG spray to eradicate MARCONS, however, growing resistance to gentamycin and poor responders to BEG have led the mold consensus network to start using ASC200 instead.
Of note, there is very little published science on MARCONS associated with chronic fatigue syndrome. Only one study is found online. More is soon to be published. However, the collective experience of 100 + health care providers who treat mold/CIRS shows a reduction in fatigue after eradication of MARCONS. Several of us are organizing another trial on MARCONS to get further studies published.
We need more research into MARCONS and MARCONS biofilms including association with nasal congestion, chronic fatigue, and facial pain.